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Diabetes and Obesity: Drugs That Help Both
 

Overweight and obesity are the major cause of Type 2 (adult onset) diabetes. According to the U.S. Centers for Disease Control and Prevention (CDC) the rate of type 2 diabetes has tripled in the last 30 years -- largely to the global obesity epidemic.

Since one of the major risk factors for type 2 diabetes is obesity, many diabetics are extremely interested in weight loss drugs. Only two weight-loss drugs, Xenical and Meridia, currently are approved for long-term use in the United States.

But the FDA currently is considering approval of a third, Acomplia, which in clinical trials has not only promoted weight loss but has aided glycemic control in newly diagnosed type 2 diabetes patients.

The other obesity drugs listed below are all intended for short-term use, and you should read the description of their side-effects carefully.

Drug Generic name Method of Action
Acomplia Rimonabant Blocks CB1 receptor in Endocannabinoid System, believed to play a critical role in the regulation of food intake and energy expenditure.
Xenical Orlistat Works in the intestines where it blocks some of the fat people eat from being absorbed and digested.
Meridia Sibutramine

Decreases appetiite by inhibiting the reuptake of serotonin, norepinephrine, and dopamine in the brain.

Ionamin Phentermine Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite
Adipex-P Phentermine Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite
Phentermine Phentermine Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite
Bontril Phendimetrazine Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite
Didrex Benzphetamine Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite
Tenuate diethylpropion Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite

 

 

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Last Updated: 07/29/2007 Copyright 2004-2006 Medical Week News, Inc. All Rights Reserved