| |
Overweight and obesity are the major cause of Type 2 (adult onset) diabetes. According to the U.S. Centers for Disease Control and Prevention (CDC) the rate of type 2 diabetes has tripled in the last 30 years -- largely to the global obesity epidemic.
Since one of the major risk factors for type 2 diabetes is obesity, many diabetics are extremely interested in weight loss drugs. Only two weight-loss drugs, Xenical and Meridia, currently are approved for long-term use in the United States.
But the FDA currently is considering approval of a third, Acomplia, which in clinical trials has not only promoted weight loss but has aided glycemic control in newly diagnosed type 2
diabetes patients.
The other obesity drugs listed below are all intended for short-term use, and you should read the description of their side-effects carefully.
| Drug |
Generic name |
Method of Action |
| Acomplia |
Rimonabant |
Blocks CB1 receptor in Endocannabinoid System, believed to play a critical role in the regulation of food intake and energy expenditure. |
| Xenical |
Orlistat |
Works in the intestines where it blocks some of the fat people eat from being absorbed and digested. |
| Meridia |
Sibutramine |
Decreases appetiite by inhibiting the reuptake of serotonin, norepinephrine, and dopamine in the brain. |
| Ionamin |
Phentermine |
Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite |
| Adipex-P |
Phentermine |
Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite |
| Phentermine |
Phentermine |
Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite |
| Bontril |
Phendimetrazine |
Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite |
| Didrex |
Benzphetamine |
Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite |
| Tenuate |
diethylpropion |
Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite |
|